Background Pain is a recognized indication of musicotherapy. Numerous studies have proved its interest in the treatment of acute or chronic pains. Sessions of personalized muscial listening directly modified the painful sensation, acting through a counter-stimulation of the afferent fibers, a diversion of the attention, a change of mood and a muscular relaxation. Other studies show correlations between muscial rhythm and the cardio respiratory frequency, and blood pressure. Description of the «U» method Musical sessions last about 20 to 40 minutes. They comprise several pieces of music, each of them lasting a few minutes, blended and linked together which slowly bring the patient to relaxation. The effect acts through a reduction of musical rhythm, orchestra formation, frequency and volume (descending phase). After a phase of maximum relaxation (lower part of the «U»), follows a re-dynamizing phase (ascending branch of the «U»). Works of instrumental music are selected concerning a various number of styles adapted the patient’s request. Musical montages are diffused in a headset in the supine position. The three-polar relation nurse —music-patient is a major tool to release emotions and allow the verbalization of pain. Conclusion Musicotherapy is a adjuvant and efficient treatment in the taking of charge of pain. This nonpharmacologic technique modifies the painful experience and its sensorial, cognitive, affective and behavioural consequences, limiting the medicinal consumption.